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Additional long-term effects of stimulant abuse include: Severe malnutrition and nutrient deficiencies from chronic appetite suppression Kidney damage and increased risk of organ failure with heavy sustained use Elevated risk of HIV and hepatitis transmission with intravenous stimulant use Lung damage associated with inhaled stimulants, particularly crack cocaine Persistent disruption to normal sleep architecture and chronic insomnia Weakened immune function and increased vulnerability to infection Stimulant-Induced Psychosis Stimulant-induced psychosis is a serious psychiatric complication of heavy stimulant use