Common prednisone side effects include: Short-Term Side Effects: Mood swings, increased appetite, fluid retention, weight gain, and difficulty sleeping
Appl In Vitro Toxicol 3:193198 Bardaweel SK, Gul M, Alzweiri M, Ishaqat A, HA AL, Bashatwah RM, (2018) Reactive oxygen species: the dual role in physiological and pathological conditions of the human body
And under the Family Smoking Prevention and Tobacco Control Act, the 2009 law that charged the FDA with regulating tobacco products, manufacturers have to persuade the agency that a modified-risk claim is not only accurate but will "benefit the health of the population as a whole, taking into account both users of tobacco products and persons who do not currently use tobacco products." That "population as a whole" standard means it's not enough to demonstrate that a product is significantly less dangerous than cigarettes
Under a federal law signed in 2020, retailers couldn't sell cigarettes and other products, such as chewing tobacco or vapes, to individuals under the age of 21