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Legalisation fulfils a 2015 campaign promise by Prime Minister Justin Trudeau, the leader of the governing Liberal Party

Abbreviations AR: Absolute increase in lifetime cancer risk CRUK: Cancer Research United Kingdom GI: Gastrointestinal HMRC: Her Majestys Revenue and Customs IARC: International Agency for Research on Cancer RR: Relative Risk UK: United Kingdom US: United States WHO: World Health Organisation YWLL: Years of working life lost References Doll R, Peto R, Wheatley K, Gray R, Sutherland I

Risk of bias assessment Only one study was classified as having low risk of bias 27 , while nearly all studies 23-26,28-33 (10 out of 11) were judged to have a high risk of bias or poor quality, primarily due to the domain of outcome measurement (Supplementary file Tables 6 and 7)

Evidence shows that there has been direct tobacco marketing to people with mental illness and other vulnerable groups of people