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Acknowledgements This research was performed within the framework of the Top Institute Pharma project T1-201 COPD, transition of systemic inflammation into multi-organ pathology, with partners University Medical Center Groningen, University Medical Center Utrecht, University Medical Center Maastricht, Nycomed BV, GlaxoSmithKline, Danone, AstraZeneca, and Foundation TI Pharma

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Even then, nicotine used in a non-combusted form, as a means of avoiding cigarette smoking, is far less hazardous to a developing fetus than continuing to smoke