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"Nicotine acts as somewhat of a stimulant and therefore interferes with your metabolism, making it work faster through a number of effects on a variety of hormones

Post-puff respiration measures on smokers of different tar yield cigarettes

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For instance, impulsive, uncontrolled behavior is seen in adults with orbitofrontal lesions [97] There is a relationship between dysfunction of the limbic system and irregularities in orbitofrontal cortex development