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There's times I've seen ones in people's collections and you can see it's got a bulging top on it, and I would contact them and ask them about it and get chatting about collections and tins and all that, and then eventually propose to them an amount of money

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The evidence from studies of children and young adults is consistent with studies in adults showing a relationship between exposure to tobacco smoke in youth and worsening lipid profiles (USDHHS 2010)

While these proposed mechanisms provide a plausible explanation for the association between smoking and ALS, further research is necessary to fully elucidate the underlying molecular pathways and confirm these hypotheses