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Cigarette smoke extract promotes nave CD4 + T-cell proliferation and differentiation by regulating GPR15 in vitro To explore the effect of cigarette smoke extract (CSE) on Th17 cell differentiation via GPR15, flow cytometric analyses were performed (Supplementary Fig

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The midbrain dopaminergic neurons receive dense cholinergic innervation from specialized brain regions that regulate reward processing and motivation

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