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Health Canada, which approved the drug for sale in 2007, has issued several warnings, telling patients and health-care professionals that it may be linked to depression, agitation, aggression, hostility and thoughts of self-harm

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It validates the American Heart Associations position that smoking is a serious health hazard, that effective multi-episode counseling and medical therapies for cessation should be available to all and that stopping smoking should be an urgent priority for smokers of all ages, especially the young, said Rose Marie Robertson, M.D., FAHA, deputy chief science and medical officer of the Association