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How nicotine replacement therapy can help young adults quit nicotine for good Nicotine replacement therapy (NRT) products such as nicotine gum, lozenges, or patches are safe, backed by science, make quitting much more comfortable, and can increase the chances of successfully quitting

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The researchers hypothesized that nicotine might act on these pacemaker neurons so as to increase the ratio of glutamate to GABA in the VTA