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In addition, smoking further exacerbates endothelial dysfunction in individuals with hypertension, diabetes, dyslipidemia, and other coronary risk factors [45]

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The contributions of recent papers, like the one cited above, increasingly call for regulators and practitioners to insist on more evidence before acting as if e-cigarettes were less harmful

a Assessments of the association between ANA and smoking status were based on a logistic regression model for ANA positivity (yes/no) that adjusted for the survey design variables (sampling weights, strata, and clusters) and categorical covariates for sex, age, and race/ethnicity