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Details on each, including the studys design, data sources, number of participants, length of follow-up, confounders adjusted for in the input data and bias covariates included in the doseresponse risk model, can be found in Supplementary Information 2 and 3

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Globally, smoking is estimated to be responsible for 8 million deaths annually, with over 1 million of those deaths being in non-smokers from the effects of passive smoking3