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The aim of this double-blind randomized placebo-controlled trial was to evaluate the efficacy and safety of varenicline (1 mg BID, administered for 12 weeks, and followed to week 24) combined with vaping cessation counseling in exclusive daily EC users intending to quit vaping

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wherein at least one of the first degradable polymer material and the second polymer material further comprises particles of starch and/or particles of cellulose