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[30] Soil degradation: Tobacco crops deplete soil nutrients more than many other crops, necessitating the heavy use of fertilizers

In a nutshell, the habit exerts a negative influence and has various adverse effects on the human health ranging from cardiovascular diseases to cancer, infectious diseases, stress, infertility, behavioral and social changes, stress, cognitive dysfunction and psychological problems

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89 FDA's Center for Drug Evaluation and Research (CDER) is generally responsible for regulating tobacco-derived products that make health or cessation (i.e., quitting) claims, such as nicotine replacement therapies (NRTs)