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Sensitivity analyses were performed by applying different threshold ages and PY in defining smoking status

Using longer-term PD models that do not require overexpression such as pre-formed fibril injections to striatum or peripheral nerves may be helpful to better understand COs effect on Syn degradation

Moreover, smoking can induce an increase in GH secretion in pregnancy due to the raised need of the foetus of a smoking mother for oxygenated blood

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