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Although we focused on FA and MD in this study due to their broad significance in overall white matter integrity, their use in most prior research (e.g., [14]), and to maintain a manageable FDR correction, it will be important for future research studies to explore the links of smoking with other white matter metrics (e.g., axial and radial diffusivity)

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Use a Tobacco Withdrawal Method Tobacco withdrawal methods, such as nicotine substitutes (patches, gums, lozenges) or anti-smoking medications prescribed by a doctor, can be useful to reduce the negative effects of tobacco withdrawal