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Although this study included both male and female mice, it did not include hormonal effects across genders and life stages as in humans such as puberty and menopause which could also influence how smoking affects endocrine functions and reproductive health 2

To stop the spread of the disease, doctors surgically removed about a third of the guitarist's tongue, but the cancer would still move into his throat, and despite receiving a clean bill of health in 2002, he occasionally submitted to operations to have cancerous cells removed from his throat