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Scientists Link Smoking to Increased Dementia Risk Research shows that smoking is a risk factor for dementia, but the good news is that giving up smoking could help reduce this risk

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Notably, nicotine reduced the mRNA transcript levels of CCL2 and CXCL2 chemokines involved in the chemotaxis of pro-inflammatory monocytes and neutrophils, respectively, in the brain of EAE mice [232]