According to a study by Helander et al., Appearance of Hexahydrocannabinols as Recreational Drugs and Implications for Cannabis Drug Testing, published in the Scandinavian Journal of Clinical and Laboratory Investigation (2024) , HHC metabolites can cross-react with THC-specific immunoassays, making detection common in urine and saliva tests
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"Because flow-mediated dilation was impaired by whole smoke, gas phase components of smoke, and plain carbon particles, with no single constituent uniquely responsible, we then explored whether the mechanism involved a common irritation response from the airway involving the vagus nerve," Springer said
