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The Minnesota Department of Health has a very informative section on the Clean Indoor Air Act

[14] [15] Use as butter flavoring [edit] Butter-flavoring controversy [edit] Chronic industrial exposure to diacetyl fumes, such as in the microwave popcorn production industry, has been associated with bronchiolitis obliterans, a rare and life-threatening form of non-reversible obstructive lung disease in which the bronchioles (small airway branches) are compressed and narrowed by fibrosis (scar tissue) and/or inflammation

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