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In addition, the FDA issued a warning in 2021 stating that the ingredients in an e-cigarette called Breathe B12 "may trigger vocal cord spasms or bronchial spasms, may be toxic to tissues in the upper respiratory tract or lower respiratory tract, or may be absorbed and produce adverse systemic effects or organ toxicity

Emphysema : This form of Chronic Obstructive Pulmonary Disease (COPD) involves damage to lung air sacs and often leads to chronic coughing