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But most of these machines have no ability to test newer products like e-cigarettes and vapes, posing a challenge to the public health agencies evaluating whether or not a product is safe enough to enter the market, said Marielle Brinkman, senior research scientist in the Division of Epidemiology at The Ohio State University College of Public Health

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Each study has added another layer of clarity, not only about whether nicotine reduction works, but how it works and how people respond