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Kim and colleagues also conducted a stratified analysis in which they looked at individuals ages 50-80 with a smoking history of 20 or more pack-years, because these individuals would be likely to be referred for lung cancer screening according to the 2021 US Preventive Services Task Force (USPSTF) and the 2023 American Cancer Society (ACS) guidelines

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It does not prove that e-cigarettes could not be of benefit if a smoker switches completely from tobacco cigarettes and uses them regularly, in the same way that FDA-approved nicotine replacement products are intended to be used. While it is generally agreed that e-cigarettes which deliver nicotine without many of the harmful products produced by burning tobacco reduce the health risks inherent in smoking cigarettes, few studies have directly investigated how useful they are in smoking cessation

The simplest way to illustrate this is to briefly discuss both the accuracy and sensitivity of standard vape alarms