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Reads plan to shield athletes from the effects of secondhand smoke, to provide smoke-free work areas for thousands of volunteers, and as Dr

This is consistent with longitudinal cohort studies from North America and Europe, which show that individuals who smoke heavily over decades experience a two- to three-fold increased risk of premature mortality 22

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Through the nAChRs in brain reward circuits, nicotine alters dopaminergic (DA) neuronal function in the ventral tegmental area (VTA) and increases dopamine release from VTA to nuclear accumbens (NA), which leads to nicotine reward, tolerance and dependence