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Thus, while hyperpolarization takes place in both ionocyte-depleted KO cultures, the response to electrically mediated depolarization is dampened in PNEC-low POU2F3 KO cultures and exaggerated in PNEC-high FOXI1 KO cultures, revealing an important contribution of PNECs to airway epithelial ion transport function

Marjorie Stewart, her character, is based on a real person and is adapted from a Damien Lewis book about a covert British organization that was founded by Prime Minister Winston Churchill and engaged in spy missions and sabotaged the German war machine in Nazi-occupied Europe during the Second World War