salt based semaglutide FDA warns about compounded versions of semaglutide, used for diabetes, weight loss semaglutide base vs salt Semaglutide:

Using biotin-probe profiling, gene knockout/knock-in models, UPLC-MS metabolomics and computational simulations, the researchers demonstrated that: CD36 binds multiple PROTAC molecules (including SIM1-Me, MZ1 and ARV-110) as well as large-molecule drugs such as rapamycin, navitoclax, birinapant, tubacin and doxorubicin, thereby promoting their cellular uptake and pharmacological activity

Tabib T, Huang M, Morse N, et al

Never store your medication near heaters, in direct sunlight, or in hot vehicles, and avoid leaving it on kitchen counters or near stoves

Its mostly water weight: Most of the weight loss in the first few days is water weight and glycogen depletion