The Beck Depression Inventory I (BDI-I) was used to evaluate depression symptoms, which assesses psychic, physical, and cognitive aspects, not including anxiety symptoms ( The Rosenberg Scale was used to assess self-esteem ( The Familiar Social and Friends Support Scale (FSFSS) was used to assess social and familiar support ( Groups The students were stratified into the following four groups to analyze self-esteem, socio-familiar support, GSH levels, and CD4 and CD8 lymphocyte counts according to PSS-10, Hamilton Anxiety Scale, and BDI-I scores: control group (participants without stress, anxiety, or depression), stress (S) group (PSS-10 score 11), stress and anxiety (SA) group (PSS-10 score 11 and Hamilton Anxiety Scale score 7), and stress, anxiety, and depression (SAD) group (PSS-10 score 11, Hamilton Anxiety Scale score 7, and BDI-I score 11)

Future studies might focus on elucidating the peptides' molecular interactions, exploring their impacts on specific cellular pathways, and assessing their potential implications in various research domains
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Discussion Treatment of TBI with neurotrophic factors holds substantial promise and this study represents the first evidence that a small molecule activator of the HGF/MET system can improve cognitive function following repeated mild TBI