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Adverse Reactions/Side Effects Generalized: Anaphylactic shock and death have been reported with administration of parenteral vitamin B 12 (see WARNINGS)

Non-injectable products offer a range of benefits, including - less invasive, - less costly, - a range of administration options that can suit personal preference, impaired swallow reflex capability, and/or enteral feeding, - administration on a daily basis which means lower doses and therefore reduced B12 peaks and troughs

doi:10.3390/nu15020261

However, it's easy to avoid vitamin B12 deficiency by recognizing if you're at risk and taking measures to avoid developing a deficiency