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studied the effect of selenium supplementation on TH concentrations in ten severely deficient subjects: Se supplementation led to a significant increase in plasma selenium concentrations and GPx activity, and this was associated with a notable decrease in plasma T4 (16%) and rT3 (29%) compared to initial values

The expression and activity of glutaminolytic enzymes, GLS and GDH, are also tightly regulated

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Moreover, an experiment on rodents found that providing Butyrate supplementation effectively reduced hippocampus inflammation and preserved hippocampal neurogenesis following RT exposure (Lee et al., 2019a)