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mean follow-up: 5.09 years) and as-treated (HR 1.07, 95% CI 0.851.36

Treating obesity requires a comprehensive and multifaceted approach that acknowledges the biological, psychological, social, and environmental factors that drive obesity, many of which are outside an individuals control, says Lisa Neff, MD, MS, a board-certified obesity medicine physician and endocrinologist with training in clinical nutrition, and executive director of global medical affairs at Eli Lilly and Company in Indianapolis

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Erianin affects the expression of cancer-associated genes by regulating pyruvate carboxylase (PC)-mediated Wnt/-catenin signaling pathway, while promoting mitochondrial oxidative stress and inhibiting glycolysis and the proliferation of liver cancer cells (20)