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van DelftRLambrechtsDVerschuurePHulsmanJMajoieM

But they appear to have a higher risk of bone fractures and a recent study suggested an increase risk of haemorrhagic stroke

Their effects likely arise from a convergence of pathways: indirectly, through systemic improvements in glycemic control and metabolism, and directly, via the activation of intraocular GLP-1Rs on cells like retinal Mller and ganglion cells, which triggers local anti-inflammatory, anti-oxidant, and anti-apoptotic responses