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Because GHK-Cu is naturally present in the body, serious adverse effects are uncommon when used under medical supervision at appropriate doses

doi: 10.1038/nri.2016.42 124 RossiA

Endocrinology 149:32943305 Reddy GR, Pushpanathan MJ, Ransom RF, Holzman LB, Brosius FC 3rd, Diakonova M, Mathieson P, Saleem MA, List EO, Kopchick JJ, Frank SJ, Menon RK (2007) Identification of the glomerular podocyte as a target for growth hormone action

The practical upshot is that the anti-inflammatory effect seems to operate even at low doses what clinicians increasingly call microdosing, which Ill return to below