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7,151,191, 6,221,367 and 5,714,167, herein incorporated by references for such disclosure, are contemplated as an additional embodiment

Studies of decompensated cirrhosis and ACLF consistently show that patients with intense systemic inflammation can improve dramatically if the precipitating event is controlled but have high competing mortality risk ( The preferential response in ALD and in patients younger than 60 years with higher baseline MELD, preserved albumin (2.5 g/dL) and no HCCdefining the ideal responder profile is biologically plausible

We have strong trial evidence that lowering atherogenic lipoproteins reduces events [6], [7]

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