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In lung adenocarcinoma (LUAD), molecular docking revealed that QUE bound to the target proteins ALDOA and CD47, suggesting that QUE binds directly to these targets, exhibiting high affinity and strong stability, thereby inhibiting these targets ( 3.2.6 Nobiletin Nobiletin (NOB), as a polymethoxyflavonoid, which is derived from citrus peel, exhibits a range of biological activities, such as inhibiting inflammatory response, antioxidant, antidiabetic and neuroprotective effects (153)

Powerful Antioxidant: Glutathione supports a robust immune system by promoting the production and function of white blood cells, which are essential for fighting off infections and diseases

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Gut microbes achieve this by synthesizing metabolites or altering their availability, underscoring tryptophans essential role as a precursor for neuroactive kynurenine pathway products, serotonin, GABA, and indoles