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In naturally aged rat ovaries, abnormal upregulation of transferrin (TF) and iron regulatory protein 2 (IRP2)-mediated transferrin receptor 1 (TfR1) leads to iron accumulation (Sze et al., 2022)

As mentioned, infectious mononucleosis caused by EBV is a risk factor for various autoimmune diseases (487, 497), and may play a potential role in ME/CFS (140, 498500)

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1076,1077 Ketone bodies such as -hydroxybutyrate and caprylic acid increase TCA cycle activity by increasing acetyl-CoA levels, independent of glycolysis