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Furthermore, these factors are at least partially expressed in vitamin A-dependent manner, though further investigations are required for elucidating in detail the role of vitamin A in defense against reactive oxygen species

The phase 2 clinical trial will enroll 150 patients with CSU, who will receive either lesigercept or a placebo for a 12-week treatment period

By targeting both structural proteins (collagen and elastin) and cellular energy systems (mitochondrial function), we can achieve unprecedented results in skin rejuvenation and overall aesthetic enhancement