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Weeks 1 to 3: Reduced pain at rest in the injured tissue

doi:10.1074/jbc.M110.172460 Kandr R, kov P, Mukov V

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Various signalling cascades, such as PI3K/Akt/mTOR, MAPK/ERK, Wnt/-catenin, the NF-B pathway, JAK/STAT pathway, and TGF- cytokine signalling, collaborate to orchestrate the proliferation, survival, invasion, and metastatic proficiency of malignant cells