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A significant decrease in plasma total glutathione (tGSH) reported in four studies from the one research group in children with autistic disorder compared to controls [4648, 50] have been confirmed by another two research groups with respect to autistic disorder [81, 82] as well as study of low functioning children with autism spectrum disorders [85] (Figure 7)

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However, the size of the benefits differed between studies, and most trials only followed patients for a short period of time (Yang et al., 2024)

[DOI] [PMC free article] [PubMed] [Google Scholar] 16.Lee S.K., Mills A