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Blokium B12 metotreksat qabul qilishdan 24 soat oldin va keyin tayinlanganda qonda oxirgisining darajasi va uning toksikligi oshishi mumkin

At the molecular level, it modulates the expression of over 4,000 human genes, roughly 6% of the genome, according to a 2012 Broad Institute Connectivity Map analysis published by Pickart, Campbell, and colleagues

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