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Moreover, numerous studies indicate that various natural metabolites can help treat ALD

Decreased serum Se concentration may lead to chronic OS through neutrophil ROS production (63)

Eulitz, V

Given the multifaceted nature of DN and its widespread implications, it is crucial for healthcare providers to recognize and address this condition through early diagnosis, effective pain management, and comprehensive care strategies aimed at improving patient outcomes and reducing the overall burden on public health systems ( 1.2 Pathophysiology and mechanisms of DN DN is a significant microvascular complication of diabetes mellitus, characterized by a range of nerve dysfunctions that can lead to debilitating symptoms such as pain, numbness, and other neurological impairments