More recently, it has been used off-label for weight loss
Retatrutide vs Tirzepatide Compared Retatrutide vs tirzepatide compared: 28.7% vs 22.5% weight loss, triple vs dual agonist mechanism, side effects, dosing, cost, and FDA status.
However, meaningful changes in body composition (fat loss) require 8-12 weeks of consistent use combined with regular exercise and a controlled diet
You might need electrolytes, Beth Israel Lahey Hospital (2024) Explore Zepbound dosing, Eli Lilly (2025) Ozempic, semaglutide injection, Novo Nordisk (2025) Wegovy prescribing information, Novo Nordisk (2025) Hypoglycemia (low blood glucose) nutrition recommendations, Cornell Health Is bone broth good for you?, MD Anderson Cancer Center (2024) Clinical recommendations to manage gastrointestinal adverse events in patients treated with GLP-1 receptor agonists: A multidisciplinary expert consensus, Journal of Clinical Medicine (2023) Managing the gastrointestinal side effects of GLP-1 receptor agonists in obesity: Recommendations for clinical practice, Postgraduate Medicine (2021) Medically accurate: SingleCares Medical Review Board analyzes all of our content to confirm its in line with current medical advice