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The presence of inflammatory mediators can also increase plasma viscosity, red blood cell aggregation and platelet activation, leading to an increase in blood flow resistance and a decrease in microcirculatory perfusion, subsequently affecting the normal function of cerebral microcirculation and reducing the supply of oxygen and nutrients (Kotan et al., 2022

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Dual-functional antioxidant ciraklc peptide discovery: A biomaterial-integrated strategy for ros scavenging and enzyme modulation in oxidative stress therapeutics