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2.5 mg per injection 25 units Frequency Daily (5 on / 2 off) Weekly Total ~12.5 mg Cycle Length 4 6 weeks ~12.5 mg/wk 5 mg per injection 15 units Frequency Daily (5 on / 2 off) Weekly Total ~25 mg Cycle Length 6 8 weeks ~25 mg/wk 5 10 mg per injection 15 30 units Frequency Daily (5 on / 2 off) Weekly Total 25 50 mg Cycle Length 6 8 weeks 25 50 mg/wk Weekly Schedule All protocols follow a 5-on / 2-off injection pattern

The data suggested that GHK may preferentially interact with hydroxyl and peroxyl radicals, while exhibiting more limited activity toward superoxide-related species