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Prior phase 2 work in MASH (F1-F3) with lower-dose semaglutide demonstrated substantial MASH resolution but a more modest impact on fibrosis, suggesting that fibrosis regression may lag or be less tightly coupled to early weight loss [8]

While it might work for US (as Sema is approved as drug) but in rest of the world, it wont as it is approved as biosimilar