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Some participants achieved weight loss of approximately 24% of body weight at 48 weeks approaching levels reported with some bariatric surgical procedures, though no direct head-to-head comparisons have been conducted and long-term durability beyond the trial period remains unknown
These findings support the notion that dietary composition and energy balance interact with endocrine and microbiota-related mechanisms, reinforcing metabolic heterogeneity in PCOS and highlighting the importance of lifestyle context in modulating glucose homeostasis
This process can compromise physical performance, slow down metabolism, and reduce overall resilience
Cognitive symptoms
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