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Due to inhibition of Adenosine Monophosphate (AMP)-Activated Protein Kinase (AMPK) increase expression of Sterol Regulatory Element-Binding Protein 1c (SREBP-1c) (Buzzetti E, et al ., 2016) that increase free Fatty Acid Synthase (FAS) and Acetyl-Coenzyme A Carboxylase (ACC), which is a rate-determining enzyme of fatty acid biosynthesis and decreased -oxidation of fatty acid (Zhang BB, et al ., 2009) resulting increase of blood TG and cholesterol and glucose level

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Zhu W, Feng PP, He K, Li SW, Gong JP