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Description

In trials directly comparing shorter- versus longer-acting GLP-1 receptor agonists, longer-acting had better glycemic efficacy

& Weening, R

A 20% infusion of Intralipid in the perfused rat ileum, however, does not significantly increase portal plasma GLP-1 from baseline (Herrmann et al., 1995), suggesting that since orally ingested fatty acids do not reach the ileum, a direct sensing mechanism for this lipid composition does not exist in the ileum or that GLP-1 in this experiment bypasses portal circulation