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Ideal candidates are those with one or more of the following: Type 2 diabetes or prediabetes, especially when lifestyle changes and other medications have been insufficient Obesity or substantial weight gain (BMI 30 kg/m, or 27 kg/m with comorbidities) Elevated cardiovascular risk (e.g., hypertension, dyslipidemia, or heart disease) Before initiating therapy, clinicians should conduct a comprehensive assessment that includes a detailed medical history, cardiovascular risk profile, weight history, and review of previous attempts at lifestyle and pharmacologic interventions
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