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e.g., under nutrient starvation, being able to provide substrates for ATP production and macromolecule synthesis (Zhang, 2013)

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We then characterized the antiviral activity of clofazimine in two cell lines that are more physiologically relevant to coronavirus diseases: cardiomyocytes derived from human embryonic stem cells and human primary small-airway epithelial cells, which robustly support SARS-CoV-2 20 and MERS-CoV 21 replication, respectively