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Losing muscle can lower the basal metabolic rate, potentially making long-term weight maintenance more difficulta phenomenon often described as metabolic adaptation. A functional medicine expert explains how looking at the root cause, not just symptoms, can help where conventional medicine often struggles

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3 Model based estimates based on a mixed model for repeated measures including treatment (and stratification factors for Study 3 only) as a factor and baseline values as a covariate

Diabetologia 39 , 15461553 (1996)