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This is in line with the higher expression of the major mitochondrial fission GTPase, dynamin-related protein 1 (DRP1) 76 (Fig

3.2 Mitochondrial metabolites as immune signaling molecules In HIV infection, mitochondrial dysfunction alters the levels of key metabolic intermediates, converting them from homeostatic signaling molecules into drivers of pathology

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The sum of long-chain acylcarnitine plasma levels in groups CAD (0.518 (0.4360.628) uM) versus non-CAD (0.683 (0.5680.860) uM) revealed significant diverse ( p = 0.024), as presented in Fig